Comparison of corticosteroid injection and ozone injection for relief of pain in chronic lateral epicondylitis


Chronic lateral epicondylitis ; injection ; corticosteroid ; ozone

Published online: May 29 2020

R. Gökhan Ulusoy, Ali Bilge, Ömür Öztürk

From the Department of Orthopaedics and Traumatology, Kafkas University, Kars, Turkey


To evaluate and compare the therapeutic effects of corticosteroid and ozone injections in the alleviation of pain associated with chronic lateral epicondylitis .

Data was collected from the medical records of 80 patients (56 women, 24 men; average age: 45.8±7.5). Corticosteroid injection was performed once a week for three times, and ozone was injected 6-8 times at 3 day intervals. No additional analgesics were given. Pain assessment was made by means of Verhaar scores before and after the first injection, on 3rd, 6th and 9th months.

The duration of pain was 24.4±12.5 months and the right side was more commonly affected (47, 58.8% vs. 33, 41.2%). Corticosteroid and ozone groups were similar with respect to age (p=0.45), gender distribution (p=0.43) and side of epicondylitis (p=0.88). Pain scores at rest, at compression and on activity were not different in two groups before and following injection. Notably, ozone group displayed better scores compared to corticosteroid in terms of pain on 3rd, 6th and 9th months after injection (p<0.001 for all).

Our results demonstrated that ozone injection can be an effective therapeutic option for CLE patients who are refractory to conservative treatment.