Experimental Research on Role of Traction Tension Affecting Wound Healing during Skin Traction Technique Performed on Pigs Specimen as Animal Models

Abstract

Objective is to investigate the role of traction tension on wound healing during skin traction experiment performed on pigs as animal models. The experimental group comprises sixteen pigs with traction tension while sixteen pigs in control group without traction tension. All healthy specimen were procured from the Experimental Animal Center of Zhengzhou University. All methods were performed in accordance with relevant guidelines of Ethics Committee of the First Affiliated Hospital of Zhengzhou University. The wound of 5-10 cm x 10 cm size was made surgically on back of pigs. Wound healing has been analyzed based on traction tension and histological staining method. Traction tension applied during skin traction technique on pig models are 1kg, 2kg, 3kg, 4kg and 5kg to analyze the wound healing speed. Data were evaluated by SPSS software. Elevated rates of skin marginal necrosis were observed under traction tension of 4 kg and 5 kg, whereas a traction tension of 3 kg is appeared to expedite wound healing. Minimal collagen fiber disruption was seen under 3Kg, whereas substantial degradation was noted under traction exceeding 3Kg. Furthermore, the applications of traction tension correlated with a discernible reduction in postoperative complications compare to specimen without traction. The magnitude of traction tension significantly modulates the wound healing speed. Pig models subjected to traction exhibited a lower incidence of complications such as necrosis, infection, inflammation, and skin scar compared to without traction.